Are you looking for a dietary supplement that can speed up your metabolism, boost energy and naturally support fat burning? Synephrine, a natural substance extracted from bitter oranges, may be just what you need. Thanks to its thermogenic effect of raising body temperature and promoting calorie burning, synephrine has become a popular ingredient in the world of fitness and dietary supplements. But what exactly is it, how exactly does it work and what can you expect from it? Let's take a look at it together.
What is synephrine?
Synephrine is a natural compound found in bitter orange. In the fruit, it serves as a defensive substance against pests. It is an alkaloid that is very similar to ephedrine, but with a milder effect.
Ephedrine is quite famous in the fitness world, it is a substance derived from theEphedraplant. It has long been used in medicine and sports to stimulate the central nervous system, increase energy and promote weight loss. However, its use in dietary supplements has been banned, mainly because of its side effects on blood pressure, tremors, heart problems and the nervous system. One of the reasons was the abuse of ephedrine as a stimulant drug and its use to make methamphetamine, known as methamphetamine. The stimulant ephedrine was also a popular doping agent, and so was placed on the list of banned substances by the International Olympic Committee. Rarely used today even in medicines, it has been replaced safelypseudoephedrine, which is a component of cold medicines - Modafen, Nurofen Stopgrip.
Synephrine is considered a safer alternative similar to epinephrine and ephedrine because it has milder effects and lowerrisk of negative effects on the heart and nervous system, while still being able to effectively boost metabolism and energy. How does it work and what can it help you with?
How does synephrine work and what are its effects?
Synephrine acts primarily on adrenergic receptors, particularly beta-3 receptors. These receptors are found in the walls of blood vessels and have the effect of dilating them (vasodilation). This mechanism of action results in an increase in blood pressure, heart rate or even lipolysis (the breakdown of fat into energy). After ephedrine was banned, scientists looked for an alternative with the same effects but with fewer risks. Synephrine proved to be an ideal candidate: unlike stronger stimulants such as ephedrine, it has a milder on the nervous system and therefore causes fewer side effects and is considered safe. Its main effects include:
Effect on fat burning and weight loss
Synephrine promotes fat burning through several key mechanisms. Its action on beta-3 adrenergic receptors stimulates the process of lipolysis. Through its action it induces thermogenesis, the body slightly increases its temperature and thus energy metabolism. In addition, synephrine slightly increases metabolic output in the resting state, which means that the body burns more calories even without physical activity. Studies have shown that p-synephrine can increase the rate of fat oxidation, the body's ability to burn fat during exercise. Women taking synephrine during exercise experienced higher burning fat compared to placebo, confirming that it can be effective during exercise and resting metabolic rate.
Studies show that it may have the best effects when combined with other substances such as caffeine. Taking it together with caffeine leads to a synergistic effect that boosts both metabolic rate and fat burning.
Effect on athletic performance
Synephrine promotes athletic performance, especially in endurance and strength sports. By its effect on fat oxidation during athletic performance, it saves glycogen stores and thus prolongs performance. This effect can be particularly noticeable during long runs or cycling. By its action on beta-3 adrenergic receptors, it may promote increased energy and concentration. Not all of its effects on athletic performance have been accurately described, however, it has beenIt is believed to be due to a combination of all the above effects. It is for these reasons that it is used in dietary supplements as part of pre-workout stimulants.
Appetite Suppression
Are you constantly plagued by cravings and hunger? Synephrine is also popular for its appetite suppressing effects, mainly due to its effects on metabolic processes. By acting on receptors, it affects energy levels and keeps the body in a slightly heightened state of alertness. This effect of synephrine can be particularly beneficial in calorie deficit, when many people experience frequent feelings of hunger. However, it should be noted that the results of studies are not always conclusive and furtherresearch to understand more precisely the mechanisms behind this effect.
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Potential effect on digestion and glycaemia
Synephrine, contained in bitter orange extract, has been used in traditional medicine to aid digestion and alleviate digestive problems. It has a mild stimulating effect on the digestive system. Studies suggest that it may accelerate bowel movements and increase the passage of digestive material through the digestive tract, promoting overall digestive efficiency.
Synephrine may affect blood glucose levels by stimulating the breakdown of glycogen into glucose, which helps to release energy. However, this effect has not been fully investigated and requires further studies to more accurately determine the effect of synephrine on glycaemia.
Safety and side effects of synephrine
Synephrine is generally considered to be a safer alternative to ephedrine, but may still have somecertain side effects, especially when combined with other stimulants such as caffeine. The main risks and side effects of synephrine include:
- Increase in blood pressure and heart rate
- Indigestion and nausea
- Nervousness and insomnia
- Drug interactions
At lower doses, side effects tend to be minimalThe risk arises when combined with other stimulants such as caffeine or medications. Everyone's individual sensitivity will also have a big impact. Before starting to take dietary supplements containing synephrine, it is advisable to consult a physician about the health status and suitability of supplementation.
What to take away from the article?
Synephrine can promote thermogenesis, fat oxidation and increased energy, which canmay be useful when trying to reduce fat or improve athletic performance. Due to its ability to act on adrenergic receptors, it affects metabolism and potentially appetite. Although synephrine is a popular dietary supplement, remember that no fat burner can replace a healthy and balanced diet. Effective weight loss requires a comprehensive approach in which a quality diet and regular exercise play a major role. Synephrine, like other fat burners, can support your efforts but is not a miracle solution. Although synephrine can help with short-term results, its long-term results are most effective when combined with a healthy lifestyle.
FAQs
How to take synephrine?
Taking 10-20 mg of synephrine daily is recommended as optimal, preferably 30 minutes before a workout. Start with a lower dose and monitor your individual body's response. If you combine synephrine in a mixture with caffeine or carnitine, do not take it just before bedtime.
How long does synephrine last?
Take synephrine 30 minutes before physical activity, its effect will be felt after about 20 minutes of training. The stimulating effect can last 4 to 6 hours, so do not take dietary supplements with synephrine just before bedtime.
What to combine synephrine with?
We commonly find synephrine in fat burners combined with stimulants along with caffeine, green tea extract or forskolin. These substances have a synergistic effect on each other.
Why can you trust us?
I am an engineer in Nutrition and Food at the Czech University of Agriculture in Prague.I am happy to help people find a balance between diet, exercise and healthy lifestyle.Writing is my passion - I like to create texts that not only inform, but also educate and inspire. I draw on my knowledge of how nutrition affects health, performance and digestive processes in the human body.
I also specialize in topics related to dietary supplements and their effect on athletic performance and overall health. During my studies, I completed semesters of anatomy and physiology at the Faculty of Physical Education and Sport of Charles University, workingwhich helped me to understand the processes in the human body and to understand the influence of proper nutrition on the performance of athletes.In my free time I enjoy travelling, volleyball and skiing.